Ultrastructural characterization of effector-target interactions for human neonatal and adult NK cells
Limitations in neonatal natural killer (NK) cell responses may be associated with the less efficient newborn capacity to solve viral infections. Although these limitations have been extensively reported they are poorly characterized. Making use of the major histocompatibility complex (MHC) class I negative cell line K562, the parameters required for the initial events involved in neonatal NK/target cell interactions were determined and compared with adult blood NK cell/target cell interactions.
Auteurs
Kenmerken
- Publicatietitel
- Ultrastructural characterization of effector-target interactions for human neonatal and adult NK cells reveals reduced intercellular surface contacts of neonatal cells
- Publicatiedatum
- 26 mei 2003
- Publicatie type
- Publicatie
- Tijdschrift
- Human Immunol 2003; 64:490-6
- Productnummer
- 91033